Penicillin
The Penicillin is a vibrant cocktail that artfully blends smoky Scotch whisky with fresh lemon juice and honey-ginger syrup, creating a harmonious balance of flavors. Served over ice and often garnished with a lemon twist, this drink offers a warming, soothing experience reminiscent of a comforting remedy. Its unique combination makes it a favorite among whisky lovers and cocktail enthusiasts alike.
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Ingredients
- 2 ozBlended Scotch
- 3/4 ozLemon Juice
- 2 tspHoney syrup
- 2 tspGinger Syrup
- 1/4 ozIslay single malt Scotch
Pairs Well With
- Roasted lamb with ginger and garlic
- Honey-glazed ham
- Spiced gingerbread
- Beef stew with root vegetables
Preparation
- 1
Shake blended Scotch, lemon juice, honey syrup and ginger syrup with ice. Strain over large ice in chilled rocks glass. Float smoky Scotch on top (be sure to use a smoky Scotch such as an Islay single malt). Garnish with candied ginger.
Best Enjoyed
Pro Tips
Use a blended Scotch as the base to provide approachable flavor without the heavy peat that can overwhelm the ginger-honey combination
Invest in quality ginger beer or make your own ginger syrup to ensure spice character and proper flavor balance
The Islay Scotch float is essential—a small pour of heavily peated whisky provides aromatic complexity without overpowering the balanced drink
Serve hot or at room temperature in a rocks glass with large ice, expressing lemon peel for brightness.
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History & Origins
The Penicillin emerged in the early 2000s as part of the craft cocktail renaissance, created at New York's Employees Only bar to showcase Scotch whisky in a warming, medicinal context. Named for its purported healing properties and the cocktail's amber-honey hue, this modern classic brilliantly demonstrates how traditional whisky cocktails can embrace contemporary ingredients like ginger and honey while maintaining classical structure. It has become the definitive template for Scotch-based warm cocktails.
Variations
Spicy Penicillin
Adds jalapeño slices and increases ginger intensity for a hotter, more assertive variation suitable for cold weather
Modern Penicillin
Incorporates lemon juice and simple syrup to create a sour-style structure with retained ginger-honey warmth
Smoky Penicillin
Uses heavily peated Islay Scotch as the base instead of blended Scotch for a smoky, medicinal intensity.
Frequently Asked Questions
Common questions about the Penicillin
The Penicillin has a flavor profile that is smoky, honeyed, citrusy, spicy. It is crafted to balance these characteristics into a harmonious, satisfying drink that appeals to a wide range of palates.
The Penicillin is ideal for cocktail parties, cozy evenings, celebrations. Its flavor profile and presentation make it a versatile choice that works equally well as a social cocktail or a relaxed evening drink.
Yes, there are several ways to adapt a Penicillin. If you cannot source Blended Scotch, look for a similar alternative that matches its flavor profile. Keep in mind that substitutions may alter the balance of the cocktail, so start with a smaller quantity and adjust to taste. The variations section above lists popular alternatives bartenders use.
Some of the most popular Penicillin variations include Spicy Penicillin, Modern Penicillin, Smoky Penicillin. Each variation puts a unique twist on the original recipe while retaining the essential character of the classic cocktail.
The Penicillin is traditionally served in a Old-fashioned glass. Using the right glassware is important because it affects the aroma, temperature retention, and overall drinking experience. If you do not have a Old-fashioned glass on hand, a similar shaped glass will work.
Yes, a mocktail version of the Penicillin is possible. Replace the base spirit with a non-alcoholic spirit alternative (there are many quality options available) and keep all other components the same. The result will capture much of the original's flavor profile while being suitable for guests who prefer alcohol-free options.
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Other Scotch Cocktails
Loch Lomond
The Loch Lomond cocktail is a refreshing blend that captures the essence of the Scottish Highlands, combining smooth Scotch whisky with zesty citrus notes and a hint of herbal complexity. Typically garnished with fresh herbs or a twist of lemon, this drink offers a perfect balance of warmth and brightness, making it an ideal choice for whisky lovers seeking a unique twist on classic flavors. Enjoy it as a sophisticated aperitif or a delightful companion to a cozy evening.
Whisky Mac
The Whisky Mac is a classic cocktail that combines the rich, warming flavors of Scotch whisky with the sweet, spicy notes of ginger wine. Typically served over ice or mixed with a splash of soda, this drink offers a delightful balance of sweetness and warmth, making it a perfect choice for any occasion. Its simple yet sophisticated profile highlights the complexity of the whisky while adding a refreshing twist from the ginger.
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